The substrate-protease pair is coexpressed at stoichiometric amounts inside a 2A-based bicistronic vector, amenable to genetic manipulation

The substrate-protease pair is coexpressed at stoichiometric amounts inside a 2A-based bicistronic vector, amenable to genetic manipulation. assay can probe PCSK9 proteolysis under conditions of either genetic or molecular perturbation inside a high-throughput manner. This system is definitely well suited for both the biochemical evaluation of clinically found out missense…

Description of terms or pathways with same color indicates similar function

Description of terms or pathways with same color indicates similar function. 12983_2020_366_MOESM5_ESM.pdf (248K) GUID:?DE78AF05-FA8E-4D84-B741-5A6DDE94E384 Additional file 6: Table S1. analysis on genes in TP-M9, TP-M10 and AS-M1 modules identified in WGCNA. Description Pentostatin of terms or pathways with same color indicates similar function. 12983_2020_366_MOESM5_ESM.pdf (248K) GUID:?DE78AF05-FA8E-4D84-B741-5A6DDE94E384 Additional file 6: Table…