While expression of Csf-1r rapidly decreased after deletion from the gene (Fig
While expression of Csf-1r rapidly decreased after deletion from the gene (Fig.?(Fig.5d,e),5d,e), HoxA9 mRNA levels had been steady at least 4?times after deletion (Fig.?(Fig.5e).5e). success time. These results reveal that PU.1-mediated upregulation of CSF-1R is certainly a crucial effector of leukemogenesis. genes such as for example genes is crucial for…