Being pluripotent VSELs express nuclear OCT-4 which is usually no longer required to maintain the pluripotent state, shifts to the cytoplasm in the immediate descendants SSCs and eventually disappears upon further differentiation

Being pluripotent VSELs express nuclear OCT-4 which is usually no longer required to maintain the pluripotent state, shifts to the cytoplasm in the immediate descendants SSCs and eventually disappears upon further differentiation. Correct meiotic progression has remained the major bottle-neck and various groups have used chemicals like retinoic acid for…

RQ-PCR analysis of the reporter gene in L-428 cells after required expression of OTX2 (right, above) and in KM-H2 cells after siRNA-mediated knockdown of OTX2 (right, below)

RQ-PCR analysis of the reporter gene in L-428 cells after required expression of OTX2 (right, above) and in KM-H2 cells after siRNA-mediated knockdown of OTX2 (right, below). Availability StatementAll relevant data are within the paper and its Supporting Information documents. Abstract In Hodgkin lymphoma (HL) we recently reported Forodesine hydrochloride…