Bulinski, and G

Bulinski, and G. such as wound healing, whereas its deregulation is a key factor contributing to tumor invasion and metastasis. Cell migration is often initiated by extracellular growth factors that activate receptor tyrosine kinase-dependent signaling, leading to extensive actin remodeling and the formation of unique structures termed membrane ruffles (18).…

Ikenoue T

Ikenoue T., Inoki K., Yang Q., Zhou X., Guan K. GST-S6K1 as the substrate. mTORC2 kinase assays were carried out at 37 C for 30 min in 25 mm HEPES (pH 7.4), 100 mm potassium acetate, 1 mm MgCl2, and 500 m ATP, with 250 ng His-Akt as the substrate.…