Downregulation of select splenic genes related to B cell differentiation, in particular Blimp1, have previously been noted in the spontaneous NZB/W_F1 model with RN486 (24), indicating that the transcriptional program related to B cell terminal differentiation may not be highly controlled by IFN
Downregulation of select splenic genes related to B cell differentiation, in particular Blimp1, have previously been noted in the spontaneous NZB/W_F1 model with RN486 (24), indicating that the transcriptional program related to B cell terminal differentiation may not be highly controlled by IFN. essential for splenic B cell terminal differentiation,…