All the results above provide further evidence supporting Notch1 as an important functional target for miR-34a in MCF-7 cells

All the results above provide further evidence supporting Notch1 as an important functional target for miR-34a in MCF-7 cells. Open in a separate window Figure 5 Notch1 restoration counteracts the inhibitory effects of microRNA-34a (miR-34a) in MCF-7 cells. (PTX) by downregulating the Notch1 pathway. Mammosphere formation and expression of the…

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[PMC free content] [PubMed] [Google Scholar] 5. with beliefs indicated. 6) and wild-type littermates (6) into sublethally irradiated Rag1?/? mice. 90 days after transplantation, three from the six Rag1?/? recipients of p52 splenocytes demonstrated higher degrees of circulating autoantibodies against dsDNA, with typically 4.4-fold increase in accordance with the Rag1?/?…