Ankyrin-1 haploinsufficiency results in reduced expression or stability of additional membrane structural parts, including band 3 and the spectrins [2,33]
Ankyrin-1 haploinsufficiency results in reduced expression or stability of additional membrane structural parts, including band 3 and the spectrins [2,33]. the manifestation or stability of additional proteins (especially the spectrins) that cooperatively bind ankyrin-1 in complexes required for appropriate function and assembly of the erythrocyte membranous-cytoskeletal network [5,6]. In mice,…