These APC were pulsed with OVA peptide and used to stimulate na?ve CD4+ OVA-specific DO11
These APC were pulsed with OVA peptide and used to stimulate na?ve CD4+ OVA-specific DO11.10 transgenic T cells. pathogenic anti-collagen II antibodies. Inhibition of IL-10 reversed the beneficial effects of AC. Passive transfer of B cells from AC-treated mice provided significant protection from arthritis. These data demonstrate that AC exert…